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Nitrofurantoin

Nitrofurantoin

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What is it?

Nitrofurantoin is an antibiotic commonly prescribed for the treatment of uncomplicated cystitis in women. Recently, nitrofurantoin has replaced trimethoprim as the first line of treatment for cystitis, as many of the bacteria that cause this condition have become less susceptible to trimethoprim. Approximately 30% of infections become resistant to trimethoprim, while resistance to nitrofurantoin is only about 3%. Nitrofurantoin is effective within the first 24 hours of treatment and can achieve complete resolution of symptoms within 3 days. If symptoms do not improve or worsen, a doctors consultation is recommended.

Composition

Nitrofurantoin is presented in the form of capsules containing 100 mg of the active substance. The composition of such capsules includes several important components that ensure the effectiveness of the drug. Firstly, it is the active substance nitrofurantoin itself, which has an antibacterial effect. The composition also includes excipients that improve the absorption and stability of the capsules.

  • Nitrofurantoin 100 mg is the main active substance.
  • Excipients - to improve stability and absorption.
  • Gelatin shell - for ease of administration and preservation of the capsule.

Each capsule is developed in accordance with high standards of safety and effectiveness. Types of packaging may vary depending on the manufacturer, but the content and composition remain unchanged, which makes nitrofurantoin a reliable choice for combating cystitis.

How to use?

To use nitrofurantoin correctly, you must follow specific instructions that will ensure maximum treatment effectiveness. It is recommended to take the medication with food or a milk drink to minimize possible gastrointestinal side effects and improve absorption of the drug.

  1. Take 100 mg twice a day at 12-hour intervals.
  2. The course of treatment is 3 days, but if there is no improvement in symptoms, a doctors consultation is necessary.
  3. Make sure you take all capsules according to the schedule to prevent re-infection.

An important feature of this antibiotic is that when taking it, the color of urine may change to dark yellow or brown. This is temporary and is not a reason to stop treatment.

How does it work?

The mechanism of action of nitrofurantoin is its ability to suppress the growth and reproduction of bacteria that cause urinary tract infections. It acts directly on the DNA of bacteria, destroying their structure and thus interrupting their life cycle. This allows the body to cope with the infection more effectively and reduce the risk of repeated exacerbations.

The antibiotic effectively fights many types of bacteria that provoke the development of cystitis, but it is especially indicated for those cases where other drugs, such as trimethoprim, are no longer as effective. Due to its ability to act on a wide range of bacterial agents, nitrofurantoin provides reliable protection and rapid results.

The effectiveness of nitrofurantoin is especially high in the first day after the start of the course of treatment. The drug can significantly reduce the severity of symptoms, such as pain and frequent urination, already in the first 24 hours of administration.

Indications

Nitrofurantoin is used to treat various urinary tract infections, especially uncomplicated cystitis in women. The drug has become one of the main means of combating this problem due to its effectiveness and safety. It is usually prescribed for short courses, which allows for rapid improvement of the condition.

  • Treatment of uncomplicated cystitis in adult women.
  • Prevention of recurrence of urinary tract infection in case of repeated episodes.
  • Use as a reserve when other antibiotics have proven ineffective.

Despite its wide range of applications, nitrofurantoin is always prescribed only after consultation with a doctor, who determines its appropriateness depending on the individual characteristics of the patient.

Contraindications

Despite its effectiveness, nitrofurantoin has a number of contraindications that must be taken into account before starting treatment. Some patients may have medical conditions in which the use of this drug will be undesirable or even dangerous. For the safety of patients, a preliminary consultation is carried out, including online, where all possible risks are clarified.

  • Patients with severe renal impairment.
  • Allergy to nitrofurantoin or capsule components.
  • Some chronic diseases that require special monitoring by a doctor.

It is important that patients familiarize themselves with the full list of contraindications and features of the use of nitrofurantoin before starting treatment in order to avoid unwanted consequences.

Side effects

Like any medication, nitrofurantoin can cause side effects that can range from mild to more serious. However, many patients tolerate it well and do not experience any unpleasant symptoms.

  • Nausea, especially if the drug is taken on an empty stomach.
  • Dizziness or mild headaches.
  • Changes in urine color (dark yellow or brown) are normal and do not require discontinuing the drug.

Patients are advised to report any unusual symptoms to their doctor so that treatment can be promptly adjusted and ensure its maximum safety and effectiveness.

Frequently asked questions

How much does Nitrofurantoin cost in pharmacies?
Price Nitrofurantoin in different pharmacies in South Africa varies.
How to buy Nitrofurantoin over the counter?
Nitrofurantoin it is available over the counter in our pharmacy.

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